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img,.rfic-single-image img{width:100%;height:auto;display:block;border-radius:8px}.rfic-card-body{padding:16px 0 4px}.rfic-card h2,.rfic-single h1{font-size:30px;padding-bottom:0px;line-height:1.05;margin:0 0 4px;color:#0c1a2a;font-weight:900}.rfic-card h3,.rfic-single h2{font-size:22px;line-height:1.15;padding-bottom:0px;margin:0 0 12px;color:#0c1a2a;font-weight:800}.rfic-labels{display:flex;flex-wrap:wrap;gap:8px;margin:6px 0}.rfic-label{padding:10px 14px;font-size:13px}.rfic-labels.is-large{gap:12px}.rfic-labels.is-large .rfic-label{font-size:clamp(0.78rem,2.2vw,1rem);padding:14px 22px;border-radius:9px}.rfic-label.active{background:#747474}.rfic-button{background:#ef7d00}.rfic-button:hover{background:#474747;color:#fff}.rfic-button{min-height:44px;padding:12px 18px;margin-top:10px}.rfic-card-actions{display:flex;gap:10px;flex-wrap:wrap}.rfic-type-recessive{background:#ef7d00}.rfic-type-incomplete-dominant{background:#00983a}.rfic-type-dominant{background:#263d73}.rfic-type-polygenic{background:#6d4b8d}.rfic-mutation-output{display:none;margin:16px 0;padding:18px;border-radius:9px;background:#f5f5f5;line-height:1.6}.rfic-mutation-output.is-visible{display:block}.rfic-single{display:grid;grid-template-columns:1fr 1fr;gap:36px}.rfic-single-content{align-self:start}@media (max-width:800px){.rfic-grid,.rfic-single{grid-template-columns:1fr}.rfic-filters{grid-template-columns:1fr 1fr}.rfic-card h2,.rfic-single h1{font-size:26px}}.rfic-grid{align-items:stretch}.rfic-card{display:flex;flex-direction:column;height:100%;box-sizing:border-box}.rfic-card .rfic-image{aspect-ratio:16/9}.rfic-card .rfic-image img{width:100%;height:100%}.rfic-card-body{display:flex;flex-direction:column;flex:1}.rfic-description{flex:1}.rfic-card-actions{margin-top:auto}.rfic-lightbox{position:fixed;inset:0;background:rgba(0,0,0,0.84);z-index:99999;display:flex;align-items:center;justify-content:center;padding:24px;cursor:zoom-out}.rfic-lightbox img{max-width:min(1100px,96vw);max-height:92vh;border-radius:8px;background:#fff}.rfic-lightbox-close{position:fixed;right:18px;top:12px;border:0;background:transparent;color:#fff;font-size:46px;line-height:1;cursor:pointer}.screen-reader-text{position:absolute !important;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}.rfic-card .rfic-label{cursor:pointer}.rfit-card-divider{border:none;border-top:2px solid #e08428;margin:0.2rem 0 0.85rem;height:0;width:100%}.rfic-type-recessive{background:#ef7d00}.rfic-type-incomplete-dominant{background:#00983a}.rfic-type-dominant{background:#7030a0}.rfic-type-polygenic{background:#2a6f9d}.rfit-card-divider{border:none;border-top:2px solid #e08428;margin:0.2rem 0 0.85rem;height:0;width:100%}.rfic-filters{display:block;margin:0 0 28px}.rfic-filter-buttons{display:flex;flex-wrap:wrap;gap:10px;align-items:center}.rfic-filter,.rfic-clear{min-height:42px;padding:10px 18px}.rfic-filter{width:var(--rfic-filter-width,auto)}.rfic-clear{display:none;margin-top:14px;padding:0;min-height:auto;background:transparent;color:#ef7d00;justify-content:flex-start}.rfic-clear.is-visible{display:inline-flex}.rfic-filter.active{background:#ef7d00;color:#fff}.rfic-card .rfic-label{padding:2px 6px;font-size:clamp(0.85rem,0.25vw,0.97rem);border-radius:8px;line-height:1.6;font-weight:300}.rfit-inline-actions{display:flex;align-items:flex-end;gap:12px;flex-wrap:wrap}.rfit-inline-actions .rfic-labels,.rfit-inline-actions .rfic-labels.is-large{display:flex;align-items:flex-end;gap:12px;flex-wrap:wrap;margin:0}.rfit-inline-actions .rfic-labels.is-large .rfic-label,.rfic-single .rfic-labels.is-large .rfic-label{min-height:32px;padding:0 16px;display:inline-flex;align-items:center;justify-content:center}.rfit-inline-actions .rfic-labels.is-large .rfic-label:hover{background-color:#474747;color:#ffffff}.rfic-lightbox-close{position:absolute;top:5px;right:5px;background:rgba(255,255,255,0.178);border-radius:50%;width:34px;height:34px;font-size:34px;font-weight:bold;color:#ef7d00;display:flex;align-items:center;justify-content:center;cursor:pointer;transition:background 0.2s ease}@media (max-width:800px){.rfic-filter-buttons{display:grid;grid-template-columns:1fr 1fr}.rfic-filter{width:100%}}.rfic-card .rfic-label.rfic-type-recessive.active{background:#ef7d00 !important}.rfic-card .rfic-label.rfic-type-incomplete-dominant.active{background:#00983a !important}.rfic-card .rfic-label.rfic-type-dominant.active{background:#7030a0 !important}.rfic-card .rfic-label.rfic-type-polygenic.active{background:#2a6f9d !important}.rfic-title,.rfic-mutation-name{display:inline;margin:0;padding:0;font:inherit;color:inherit}.rfic-lightbox{cursor:zoom-out}.rfic-lightbox-inner{position:relative;display:inline-block;max-width:min(1100px,96vw);max-height:92vh}.rfic-lightbox .rfic-lightbox-inner img{display:block;max-width:100%;max-height:92vh;border-radius:8px;background:#fff}.rfic-lightbox-close{position:absolute;top:5px;right:5px;background:rgba(255,255,255,0.178);border-radius:50%;width:34px;height:34px;font-size:34px;font-weight:bold;color:#ef7d00;display:flex;align-items:center;justify-content:center;cursor:pointer;transition:background 0.2s ease}@media (max-width:600px){.rfic-lightbox-close{}}.rfic-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:28px;align-items:stretch}.rfic-card{display:flex;flex-direction:column;height:100%;box-sizing:border-box}.rfic-card-inner{display:flex;flex-direction:column;height:100%;width:100%}.rfic-card-body{display:flex;flex-direction:column;flex:1 1 auto}.rfic-card-header{display:flex;flex-direction:column}.rfic-card-title,.rfic-card-subtitle{display:-webkit-box;-webkit-box-orient:vertical;overflow:hidden}.rfic-card-title{-webkit-line-clamp:2}.rfic-card-subtitle{-webkit-line-clamp:1;min-height:1.15em}.rfic-card .rfit-card-divider{margin-top:auto;flex:0 0 auto}.rfic-card-description-wrapper{position:relative;margin:12px 0}.rfic-card .rfic-description,.rfic-card-description{display:-webkit-box;-webkit-line-clamp:5;-webkit-box-orient:vertical;overflow:hidden;line-height:1.65;margin:0;flex:0 0 auto}.rfic-card-description-wrapper.has-more .rfic-card-description{padding-right:5.6em}.rfic-card-more{display:none;position:absolute;right:0;bottom:0;border:0;padding:0 0 0 0.35em;margin:0;background:#f6f6f6;color:#e08428;cursor:pointer;font:inherit;font-weight:700;line-height:1.65}.rfic-card-more.is-visible{display:inline}.rfic-card-more:hover{filter:brightness(1.08)}@media (max-width:980px){.rfic-grid{grid-template-columns:repeat(2,minmax(0,1fr))}}@media (max-width:800px){.rfic-grid{grid-template-columns:1fr}}.rfic-card h5.rfic-card-title,.rfic-card h4.rfic-card-subtitle{padding:0;color:#0c1a2a}.rfic-card h5.rfic-card-title{font-size:clamp(1.1rem,1vw,1.3125rem);line-height:1.05;margin:0 0 4px;font-weight:900}.rfic-card h4.rfic-card-subtitle{font-size:clamp(0.96rem,0.3vw,1.05rem);line-height:1.15;margin:0 0 12px;font-weight:800}.rfic-card-title,.rfic-card-subtitle{display:block !important;-webkit-line-clamp:unset !important;-webkit-box-orient:initial !important;overflow:visible !important;min-height:0 !important}.rfic-card .rfit-card-divider{margin:0.2rem 0 0.85rem !important;flex:0 0 auto}.rfic-card-description-wrapper{position:relative;margin:0 0 12px 0}.rfic-card .rfic-description,.rfic-card-description{display:-webkit-box;-webkit-line-clamp:4;-webkit-box-orient:vertical;overflow:hidden;line-height:1.65;margin:0;flex:0 0 auto;padding-right:0 !important}.rfic-card-description-wrapper.has-more .rfic-card-description{padding-right:0 !important}.rfic-card-more{display:none !important}@media (max-width:800px){.rfic-card h5.rfic-card-title{font-size:26px}.rfic-card h4.rfic-card-subtitle{font-size:20px}}.rfic-card-footer{margin-top:auto;display:flex;flex-direction:column}.rfic-card .rfic-card-footer .rfic-labels{margin:0 0 8px 0}.rfic-card .rfic-card-footer .rfic-card-actions{margin-top:0}.rfic-card-title-link{color:inherit;text-decoration:none}.rfic-card-title-link:hover,.rfic-card-title-link:focus{color:inherit;text-decoration:none}.rfic-label-static{cursor:default;pointer-events:none}.rfic-label-static{cursor:default !important;pointer-events:none}.rfic-label-static:hover,.rfic-label-static:focus,.rfic-label-static.active{filter:none !important;box-shadow:none !important}.rfic-filter-buttons{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;align-items:stretch;width:100%}.rfic-filter{width:100%;min-width:0;min-height:46px;padding:10px 10px;white-space:nowrap !important;overflow:hidden;text-overflow:ellipsis;font-size:clamp(0.78rem,2.2vw,1rem);line-height:1}@media (min-width:768px){.rfic-filter-buttons{grid-template-columns:repeat( auto-fit,minmax(var(--rfic-filter-width,160px),1fr) )}}.rfic-single{align-items:end;margin-bottom:28px}.rfic-mutation-output{margin-top:0;margin-bottom:28px}